| Yuji Ozeki, Toshifumi Tomoda, John Kleiderlein, Atsushi Kamiya,
Lyuda Bord, Kumiko Fujii, Masako Okawa, Naoto Yamada,
Mary E. Hatten, Solomon H. Snyder, Christopher A. Ross, Akira Sawa |
| Disrupted-in-Schizophrenia-1(DISC-1) : Mutant truncation prevents binding to NudE-like(NUDEL)and inhibits neurite outgrowth. |
| Proc Natl Acad Sci U S A. 2003;100(1):289-294
PMID: 12506198
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| 曄堎偵傛傝愗抐偝傟偨Disrupted-in-Schizophrenia-1乮DISC-1乯偼 NudE-like乮NUDEL乯偲寢崌偱偒偢丄恄宱撍婲偺怢挿傪慾奞偡傞 |
亂梫巪亃
摑崌幐挷徢乮惛恄暘楐昦乯偺尨場傪夝柧偟丄帯椕朄傗梊杊朄傪妋棫偡傞偙偲偼丄惛恄堛妛偺戝偒側栚昗偺堦偮偱偡丅夁嫀悢廫擭偵傢偨偭偰丄 偙偺崲擄側幘姵偵懡偔偺尋媶幰偑挧愴傪懕偗偰偒偨寢壥丄偙偺昦婥偵娭偡傞偨偔偝傫偺忣曬偑愊傒廳側偭偰偒偰偄傑偡丅 偟偐偟巆擮側偑傜丄尰嵼偺偲偙傠傑偩幘姵偺尨場傪夝柧偡傞偵帄偭偰偄傑偣傫丅変乆偼偙偆偟偨栤戣傪夝寛偡傞偨傔偵丄尋媶傪懕偗偰偄傑偡丅
崱夞偺尋媶偼DISC1偲偄偨傫傁偔幙偺摥偒傪挷傋偨傕偺偱偡丅僗僐僢僩儔儞僪偺偁傞壠宯偺恖偨偪偼丄 DISC1偲偄偆偨傫傁偔幙傪嶌傞偨傔偺堚揱忣曬偑夡傟偰偄偰丄堎忢側DISC1偟偐嶌傞偙偲偑偱偒側偄偲梊應偝傟偰偄偨偺偱偡偑丄 偙偺堎忢傪傕偭偰偄傞恖偼丄摑崌幐挷徢偵偐偐傝傗偡偐偭偨偺偱偡丅偙偺偨傫傁偔幙偺摥偒偼枹抦偺傕偺偱偁偭偨偺偱丄 偙偺偨傫傁偔幙偺摥偒傪挷傋傟偽丄摑崌幐挷徢偺尨場傪柧傜偐偵偡傞忣曬傪摼傞偙偲偑偱偒傞偺偱偼側偄偐偲峫偊偰丄尋媶傪巒傔傑偟偨丅
尋媶偺寢壥丄僱僘儈乮儔僢僩乯偺擼偱偼丄偙偺偨傫傁偔幙偼戀帣婜傗梒彮婜偵懡偔嶌傜傟偰偄傞偙偲丄 嵶朎偺堏摦傗宍懺偲娭楢偡傞偄偔偮偐偺偨傫傁偔幙乮NUDEL側偳乯偲寢崌偡傞偙偲丄 偝傜偵偼恄宱嵶朎偵帡偨撍婲傪怢偽偡攟梴嵶朎偺拞偵姵幰偝傫偲摨偠堎忢側DISC1傪嶌傜偣傞偲丄撍婲偺惉挿偑偍偒偵偔偔側傞偙偲傪尒偮偗傑偟偨丅偙偆偟偨寢壥偐傜丄DISC1偲偄偆偨傫傁偔幙偼丄擼側偳偺恄宱偺敪払偵娭學偑偁傞偲偺悇應傪偟傑偟偨丅忋偱弎傋偨偲偍傝丄 偙傟傑偱偵摑崌幐挷徢偵娭偡傞懡偔偺忣曬偑廤傑偭偰偒偰偄傑偡丅偦偺忣曬偵傛傞偲丄摑崌幐挷徢偵側傞尨場偼戀帣偐傜弌嶻偺崰偵偡偱偵偁偭偰丄 偦偺惓懱偼丄恄宱偺敪払偺寉偄忈奞偱偁傞偲峫偊傜傟偰偄傑偡偑乮恄宱敪払忈奞壖愢偲偄偄傑偡乯丄 枹抦偺偨傫傁偔幙偱偁偭偨DISC1偺摥偒傪挷傋偨変乆偺尋媶偼丄偙偺恄宱敪払忈奞壖愢偲柕弬偟側偄撪梕偱偡丅 偦傟偳偙傠偐丄DISC1偼偙傟傑偱幚嵺偵偼偳偺傛偆側儊僇僯僘儉偵側偭偰偄傞偺偐柧傜偐偱側偐偭偨恄宱敪払忈奞壖愢傪丄 弶傔偰嬶懱揑偵愢柧偡傞僞儞僷僋幙偺傂偲偮偱偁傞壜擻惈偑崅傑偭偨偺偱偡丅
変乆偼崱屻傕偙偺偨傫傁偔幙偺摥偒傪徻偟偔挷傋傞偙偲偑丄摑崌幐挷徢偺尨場傪扵傞忋偱廳梫偱偁傞偲峫偊偰偄傑偡丅 傑偨摨帪偵丄姵幰偝傫偵偛嫤椡傪偄偨偩偒側偑傜丄戞擇丄戞嶰偺DISC1傪扵偡搘椡傪奐巒偟偰偄傑偡丅
暥愑丂惛恄壢恄宱壢丂旜娭丂桽擇 |
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