| Takuya Fujita, Koji Teramoto, Yoshitomo Ozaki, Jun Hanaoka, Noriaki Tezuka, Yasushi Itoh,
Tohru Asai, Shozo Fujino, Keiichi Kontani, Kazumasa Ogasawara |
| Inhibition of transforming growth factor-兝-mediated immunosuppression in tumor-draining lymph nodes augments antitumor responses by various immunologic cell types |
| Cancer Research, 2009, 69(12), 5142-50, PMID: 19491278 |
|
| 庮釃強懏儕儞僷愡偵偍偗傞TGF-兝偺婡擻慾奞偵傛傞峈庮釃柶塽墳摎偺憹嫮岠壥 |
亂梫巪亃
庮釃強懏儕儞僷愡偼慡恎惈偺峈庮釃柶塽墳摎傪桿摫偡傞忋偱嵟傕廳梫側晹埵偱偁傞丅
偟偐偟丄扴娻屄懱偵偍偄偰偼庮釃慻怐傛傝暘斿偝傟傞柶塽梷惂惈僒僀僩僇僀儞transforming growth factor-兝 (TGF-兝)偑庮釃強懏儕儞僷愡偵棳擖偟峈庮釃柶塽墳摎偺桿摫傪梷惂偟偰偄傞丅
変乆偼庮釃強懏儕儞僷愡偵偍偗傞TGF-兝偵傛傞柶塽梷惂偵拝栚偟丄摨晹埵偱偺TGF-兝偺婡擻傪慾奞偡傞偙偲偱慡恎惈偺峈庮釃柶塽墳摎偑憹嫮偡傞偐偳偆偐扴娻儅僂僗儌僨儖偱専摙偟偨丅庮釃強懏儕儞僷愡嬊強偱偺TGF-兝偺婡擻慾奞偺偨傔偵偼僾儔僗儈僪儀僋僞乕僔僗僥儉傪梡偄偨丅TGF-兝偺2宆儗僙僾僞乕偺嵶朎奜僪儊僀儞傪僐乕僪偡傞僾儔僗儈僪儀僋僞乕(TGFR DNA)傪嶌惢偟丄扴娻儅僂僗偺庮釃慻怐嬤朤偺嬝擏撪偵愙庬偡傞偲丄僾儔僗儈僪儀僋僞乕傪庢傝崬傫偩嬝嵶朎偼壜梟惈TGF-兝 2宆儗僙僾僞乕傪暘斿偟丄偙傟偼嬤朤偺庮釃強懏儕儞僷愡偵棳擖偟偰TGF-兝偺婡擻傪慾奞偡傞丅儅僂僗儕儞僷庮嵶朎姅E.G7傪懁暊晹偵旂壓堏怉偟偨扴娻儅僂僗偵偍偄偰丄TGFR DNA偱庮釃強懏儕儞僷愡偱偺TGF-兝偺婡擻傪慾奞偡傞偲丄庮釃強懏儕儞僷愡偵偍偄偰惂屼惈T嵶朎偺憹怋偑梷惂偝傟庮釃峈尨摿堎揑偵僀儞僞乕僼僃儘儞僈儞儅傪嶻惗偡傞CD4梲惈嵶朎偲CD8梲惈嵶朎偑憹壛偟偨丅庮釃強懏儕儞僷愡偵偍偄偰憹嫮偟偨峈庮釃柶塽墳摎偼慡恎惈偵塭嬁傪媦傏偟丄嵶朎彎奞惈T嵶朎偺憹壛丄NK妶惈偺憹嫮丄庮釃峈尨偵懳偡傞峈懱壙偺忋徃偵娭梌偟偨丅 偙傟傜條乆側柶塽扴摉嵶朎偺憤崌揑側摥偒偵傛偭偰旂壓堏怉偟偨E.G7庮釃偺憹怋偼梷惂偝傟偨偑丄儅僂僗埆惈崟怓庮B16F10攛揮堏儌僨儖偺攛揮堏憙偵偍偄偰傕峈庮釃岠壥傪擣傔丄桿摫偝傟偨慡恎惈偺峈庮釃柶塽墳摎偺嫮椡偝偑帵偝傟偨丅偙傟傜偺寢壥偼庮釃偵懳偡傞峈TGF-兝椕朄偺嶌梡揰傪傛傝柧妋偵偟偨傕偺偱丄崱屻偺TGF-兝傪昗揑偵偟偨娻暘巕昗揑帯椕朄偺奐敪偵桳梡偱偁傞偲峫偊傜傟偨丅
暥愑丂屇媧婍奜壢丂帥杮丂峎帯
|
|
